EDUCATION:

BS, Bacteriology, University of Wisconsin-Madison, 1997
PhD, Nutritional Sciences/Bacteriology, University of Wisconsin-Madison, 2006
Postdoc, Aging/Caloric Restriction, University of Wisconsin-Madison, 2006-2009

TEACHING:

RECENT PUBLICATIONS:

Porras AM, Shanmuganayagam D, Meudt JJ, Krueger CG, Hacker TA, Rahko PS, Reed JD, Masters KS. 2015. Development of Aortic Valve Disease in Familial Hypercholesterolemic Swine: Implications for Elucidating Disease Etiology. J Am Heart Assoc. 2015 Oct 27;4(10).

Polewski MA, Burhans MS, Zhao M, Colman RJ, Shanmuganayagam D, Lindstrom MJ, Ntambi JM, Anderson RM. Plasma diacylglycerol composition is a biomarker of metabolic syndrome onset in rhesus monkeys. J Lipid Res.Aug;56(8):1461-70.

Wentland, A.L., O. Wieben, D. Shanmuganayagam, C.G. Krueger, J. J. Meudt, D. Consigny, L. Rivera, P.E. McBride, J.D. Reed, T.M Grist. Measurements of wall shear stress and aortic pulse wave velocity in swine with familial hypercholesterolemia. J Magn Reson Imaging. 2015 May;41(5):1475-85.

Porras AM, Shanmuganayagam D, Meudt JJ, Krueger CG, Reed JD, Masters KS. Gene Expression Profiling of Valvular Interstitial Cells in Rapacz Familial Hypercholesterolemic Swine. Genom Data. 2014 Dec 1;2:261-263.

Feliciano RP, Meudt JJ, Shanmuganayagam D, Metzger BT, Krueger CG, Reed JD.Supercritical fluid extraction (SFE) of cranberries does not extract oligomeric proanthocyanidins (PAC) but does alter the chromatography and bioactivity of PAC fractions extracted from SFE residues. J Agric Food Chem. 2014Aug 6;62(31):7730-7.

Johnson LL, Tekabe Y, Kollaros M, Eng G, Bhatia K, Li C, Krueger CG, Shanmuganayagam D, Schmidt AM. Imaging RAGE expression in atherosclerotic plaques in hyperlipidemic pigs. EJNMMI Res. 2014 Jun 11;4:26.

Pierre, J.F, A.F. Heneghan, R.P. Feliciano, D. Shanmuganayagam, C.G. Krueger,  J.D. Reed, K.A. Kudsk. Cranberry proanthocyanidins improve intestinal sIgA during elemental enteral nutrition.J Parenter Enter Nutr.. 2014; 38:107-114.

Feliciano, R.P., J.J. Meudt, D. Shanmuganayagam, C.G. Krueger and J.D. Reed.  Ratio of “A-type” to “B-type” proanthocyanidin interflavan bonds affects extraintestinal Pathogenic Escherichia coli invasion of gut epithelial cells. J Agric Food Chem. 2013; Web Publication

Heneghan AF, Pierre JF, Tandee K, Shanmuganayagam D, Wang X, Reed JD, Steele JL, Kudsk KA. Parenteral nutrition decreases paneth cell function and intestinal bactericidal activity while increasing susceptibility to bacterial enteroinvasion. J Parenter Enteral Nutr. 2013 Sep;38(7):817-24.

Pierre, J.F, A.F. Heneghan, J.M. Meudt, M.P. Shea, C.G. Krueger, J.D. Reed, K.A.  Kudsk, D. Shanmuganayagam. Parenteral nutrition increases susceptibility of ileum invasion by E. coli. J Surg Res. 2013; 183: 583-591.

Pierre, J.F, A.F. Heneghan, R.P. Feliciano, D. Shanmuganayagam, D.A.  Roenneburg, C.G. Krueger, J.D. Reed, K.A. Kudsk. Cranberry proanthocyanidins improve the gut mucous layer morphology and function in mice receiving elemental enteral nutrition. J Parenter Enter Nutr. 2013; 37: 401-409.

Feliciano, R.P., C.G. Krueger, D. Shanmuganayagam, M. M. Vestling, J. D. Reed.  Deconvolution of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry isotope patterns to determine ratios of A-type to B-type interflavan bonds in cranberry proanthocyanidins. Food Chem. 2012; 135:1485-1493. 

Feliciano, R.P., M.P. Shea, D. Shanmuganayagam, C.G. Krueger, A.B. Howell, J.D. Reed. Comparison of Isolated Cranberry (Vaccinium macrocarpon Ait.) Proanthocyanidins to Catechin and Procyanidins A2 and B2 for Use as Standards inthe 4-(Dimethylamino)cinnamaldehyde Assay. J Agric Food Che. 2012; 60:4578- 85.

Ge W, Krueger CG, Weichmann AJ, Shanmuganayagam D, Varghese T. Displacement and strain estimation for evaluation of arterial wall stiffness using a familial hypercholesterolemia swine model of atherosclerosis. Medical Physics 2012; 39 (7): 4483-92.

Shanmuganayagam, D., M. Beahm, M. Kuhns, C.G. Krueger, J. Reed, J. Folts. Differential effects of grape (Vitis vinifera) skin polyphenolics on human platelet aggregation and low-density lipoprotein oxidation. J Agric Food Chem 2012; 60:5787-5794.

Tsao FH, Culver B, Pierre J, Shanmuganayagam D, Patten C, Meyer KC.Effect of prophylactic supplementation with grape polyphenolics attenuates endotoxin-induced serum secretory phospholipase A2 activity in rats.
Comparative Medicine 2012; 62(4): 271-278.

PATENTS & APPLICATIONS

Tannin-containing gastrointestinal formulations and methods of use
Publication date: 2014-07-14 Publication number: US20140200266A1